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L-CARNITINE
 
  Health Supplements Limitations And Applications

The available research on L-carnitine supplementation does not appear to support claims of enhanced aerobic or anaerobic exercise performance. While it is true that carnitine plays a vital role in energy metabolism, additional carnitine from exogenous sources does not appear to yield any benefit above and beyond the necessary physiological dose.
Results from experimental data on dietary supplements must be judiciously applied given the limitations of the research methods employed. Many authors note that 'highly trained subjects' were used. However, there is no uniform definition for training status. A 'highly trained' athlete in one study may be a 'moderately-conditioned' athlete in another, and vice-versa.




Products containing L-carnitine cannot be marketed as "natural health products" in Canada, since L-carnitine is not considered a natural ingredient. L-carnitine products and supplements are not allowed to be imported into the country (Health Canada).
  Effects on Diabetes
L-Carnitine improved glucose disposal among 15 patients with Type II Diabetes and 20 healthy volunteers. Glucose storage increased between both groups, but glucose oxidation increased only in the diabetic group. Finally, glucose uptake increased about 8% for both.

External links

. Article on Carnitine
. Molecule of the Month
. Carnitine Team
. Why Carnitine?
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. Applications
. Studies



  Production

It can be synthesised within the body from the amino acids lysine or methionine. Vitamin C (ascorbic acid) is essential to the synthesis of carnitine.

It has been speculated that during growth or pregnancy the requirement of carnitine could exceed its natural production.